Calming Spot On naturally and effectively calms and reduces problem behavior in cats of all breeds and ages. Containing Valerian Extract, a single application will calm the cat for up to one week. Animals & Pet Supplies > Pet Supplies > Pet Medicine Calming Spot On for cats can help alleviate problems such as: destructive behavior and inappropriate marking. It will also help the cat feel less apprehensive during difficult times such as visits to the vet or kennels, fireworks, thunderstorms, travelling in the car, or moving house.